Hypergonadotropic Hypogonadism (HHG) is a condition typified by defective gonadal development and/or function, as a result of elevated levels of gonadotropins. In terms of symptoms, HHG may be very similar to the condition Hypergonadotropic Hypogonadism. However, the underlying cause is the exact opposite. A simple test to measure the levels of gonadotropins in the serum is enough to distinguish between these two conditions. However, differentiating between HHG and constitutional delay in growth is more difficult. This is especially true, if no family history is available.
Treatment involves management with sex steroids; ethinyl estradiol followed by a progestational agent for girls, and testosterone enathate along with human chorionic gonadotropin for boys. Most patients can achieve fertility with the help of hormone treatment.