GATA3 is a member of the GATA family of dual zinc-finger transcription factors. This dual zinc finger transcription factor binds DNA with its C-terminal zinc finger (ZnF2) and stabilizes this binding with its N-terminal zinc finger (ZnF1). ZnF1 also interacts with other zinc finger proteins, notably Friend of GATA (FOG). The two zinc fingers of GATA3 are encoded by 2 separate exons highly conserved with those of GATA1.