WNT7A is a member of the WNT family, which is involved in cell signaling and plays an important role in cancer development. WNT7A functions as a ligand for members of the frizzled family of seven transmembrane receptors. It is probably a developmental protein, it also guides the development of the anterior-posterior axis in the female reproductive tract, plays a critical role in uterine smooth muscle pattering, maintains the adult uterine function, and it also responds to changes in the levels of sex steroid hormone in the female reproductive tract.

WNT7A gene mutations result in limb pelvis hypoplasia aplasia syndrome (LPHAS) and Fuhrmann syndrome (FUHRS).