The Golgi Apparatus is a membrane bound cell organelle that is involved in the modifying, sorting, and packaging of proteins for secretion. The GM130 protein, encoded by the GOLGA2 gene, is an important component of this organelle and plays a key role in maintaining its structure. The protein acts as a vesicle tether and helps with the fusion of the vesicle at the Golgi membrane. It is also involved in mitotic Golgi disassembly, spindle pole assembly, centrosome organization, Golgi ribbon formation, and glycosylation of membrane and secretory proteins. Deficiency of the GOLGA 2 protein can thus negatively affect the Golgi Apparatus, resulting in its fragmentation.