The GORAB gene provides instructions for making a member of the golgin family that localizes to the Golgi complex and the cytoplasm.  The golgin family consists of a group of coiled-coil proteins that play different roles in Golgi-related transport processes.  The GORAB protein interacts with the GTP-bound form of the small Ras-like GTPase RAB6.  It has also been shown to interact with the SCYL1, MDM2, and PIRH2 protein.  Studies in mice models have shown that the protein plays a major role in hair follicle morphogenesis by modulating follicular keratinocyte differentiation via the hedgehog signaling pathway.  It has also been speculated to play a role in the secretory pathway and in mitosis by interacting with the N-terminal kinase-like protein. 

Defects in this protein have been associated with Geroderma Osteodysplastica, a disorder characterized by wrinkled skin, lax, joint laxity and a prematurely aged face appearance.