The BTN3A2 gene encodes the Butyrophilin Subfamily 3 Member A2 protein, a member of the immunoglobulin superfamily. The protein is an integral component of the plasma membrane and contains 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. BTN3A2 is involved in interferon gamma secretion and is believed to play an important role in the T cell mediated adaptive immune response.