The TADA1 gene encodes a protein subunit of the STAGA complex. Other proteins involved in this complex include SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9. The STAGA complex is an acyl-CoA-dependent transcriptional coactivator that is involved in transcriptional regulation, DNA damage repair and chromatin modification via histone H3 acetylation.