The RGL1 gene encodes Ral Guanine Nucleotide Dissociation Stimulator-Like 1, a protein that belongs to the Guanine Nucleotide Dissociation Stimulators (GDSs) family along with other proteins such as RALGDS. GDSs are effectors of Ras-related GTPases and participate in various cell signaling pathways. The function of the RGL1 protein is yet to be fully elucidated. However, similar to RALGDS, it is believed to have Ral guanyl-nucleotide exchange factor activity and is involved in Ras and Ral signaling pathways.