The mitochondrial ribosome is a protein complex that is essential for the translation of 13 mitochondrial proteins. The ribosome is encoded by the nuclear genome and is made up of two subunits: a smaller 28S subunit and a larger 39S subunit. The smaller 28S subunit is encoded by the MRPS35 gene. As part of the ribosome, the MRPS35 protein is thus involved in the biological processes of mitochondrial translational elongation, mitochondrial translational termination and DNA damage response.