The RILPL2 gene encodes RAB-Interacting Lysosomal Protein-Like 2. As its name states, this protein is similar to the RILP protein and it consists of two RILP homology domains. The RILPL2 protein is not fully characterized and its function is yet to be completely understood. However, studies of its lower ortholog genes have helped elucidate possible roles it may play. It has been suggested to be involved in epithelial cell morphogenesis, cilium assembly and neuronal morphogenesis, regulating the organization of dendritic spines. It is also believed to be involved in cellular protein transport, particularly in the transport of proteins from the ciliary membrane to the plasma membrane.