The RIMS2 gene encodes a large cellular protein consisting of an N-terminal zinc-binding domain, a PDZ domain, a C2A domain, a PxxP motif and a C-terminal C2B domain. While the protein is yet to be fully characterized, its potential role has been inferred through lower ortholog studies. RIMS2 has thus been suggested to function as a Rab effector involved in exocytosis, particularly synaptic membrane exocytosis and calcium ion-regulated exocytosis of neurotransmitter. It is also believed to function in the biological processes of cAMP mediated signaling, insulin secretion, regulation of dendrite extension, regulation of excitatory/inhibitory postsynaptic potential and spontaneous neurotransmitter secretion.