IgA Nephropathy, Susceptibility to, 1

Alternative Names

  • IGAN1
  • IGAN
  • Nephritis, IgA type
  • Berger Disease
Back to search Result
WHO-ICD-10 version:2010

Diseases of the genitourinary system

Glomerular diseases

OMIM Number

161950

Mode of Inheritance

?Autosomal dominant

Gene Map Locus

6q22-q23

Description

Globally, IgA nephropathy is one of the leading causes of glomerulonephritis and end-stage renal disease. However, its pathogenesis remains unclear. The condition is characterised by hematuria and proteinuria, and about one-third of affected patients progress to renal failure. 

Epidemiology in the Arab World

View Map

Other Reports

Lebanon

Karnib et al. (2007), studied a large consanguineous Lebanese-Druze family with 16 affected individuals. Symptoms ranged from isolated hematuria to advanced renal failure. While an autosomal dominant inheritance was considered likely, the authors did not find evidence of linkage to known loci.  

© CAGS 2024. All rights reserved.