Deafness (DFN), Autosomal Recessive (B) 14 (DFNB14) belongs to a large group of genetically heterogeneous hearing loss disorders. DFNB14 defines a genetic locus shown through linkage and fine mapping studies in multiple families to be inherited in individuals affected with profound bilateral hearing loss.
Mustapha et al. (1998) described three children from a consanguineous family affected with prelingual, profound, sensorineural hearing loss. Linakge analysis in the family localized the caual gene to a 15cM locus on chromosome 7q31.