Cranio-lenticulo-sutural dysplasia (CLSD), also known as Boyadjiev-Jabs syndrome, is a rare autosomal recessive syndrome manifesting with large and late-closing fontanels, hypertelorism, early-onset cataract and mild generalized skeletal dysplasia. Affected patients have abnormal hair, frontal bossing, hyperpigmentation with capillary hemangioma of the forehead, macrocephaly, significant hypertelorism, and a broad and prominent nose.
CLSD was first reported in 21 members of a Saudi family. Treatment is mainly symptomatic and the prognosis is good.