Steroid Sulfatase

Alternative Names

  • STS
  • Arylsulfatase C
  • ARSC
  • Estrone Sulfatase
  • Steroid Sulfatase, Isozyme S, Included

Associated Diseases

Ichthyosis, X-Linked
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OMIM Number

300747

NCBI Gene ID

412

Uniprot ID

P08842

Length

207,352 bases

No. of Exons

16

No. of isoforms

1

Protein Name

Steryl-sulfatase

Molecular Mass

65492 Da

Amino Acid Count

583

Genomic Location

chrX:7,147,289-7,354,640

Gene Map Locus
Xp22.31

Description

This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. [From RefSeq]

Epidemiology in the Arab World

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