Fibroblast Growth Factor, Acidic, Intracellular Binding Protein

Alternative Names

  • FIBP
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OMIM Number

608296

NCBI Gene ID

9158

Uniprot ID

O43427

Length

4,771 bases

No. of Exons

10

No. of isoforms

2

Protein Name

Acidic fibroblast growth factor intracellular-binding protein

Molecular Mass

41878 Da

Amino Acid Count

364

Genomic Location

chr11:65,883,739-65,888,509

Gene Map Locus
11q13.1

Description

Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. [From RefSeq]

Epidemiology in the Arab World

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Variant NameCountryGenomic LocationClinvar Clinical SignificanceCTGA Clinical Significance Condition(s)HGVS ExpressionsdbSNPClinvar
NM_004214.5:c.175_176insTAAUnited Arab EmiratesNC_000011.10:g.65888042_65888043insTTAPathogenicPathogenicThauvin-Robinet-Faivre SyndromeNG_047103.1:g.5497_5498insTAA; NM_004214.5:c.175_176insTAA; NP_004205.2:p.His59delinsLeuAsn886037928254242
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