ADP Ribosylation Factor Like GTPase 15

Alternative Names

ARL15
ADP-Ribosylation Factor-Related Protein 2
ARFRP2
ADP-Ribosylation Factor-Like Protein 15
ADP-Ribosylation Factor Like GTPase 15
FLJ20051

Length

426,649 bases

No. of Exons

No. of isoforms

Protein Name

ADP-ribosylation factor-like protein 15

Molecular Mass

22876 Da

Amino Acid Count

204

Genomic Location

chr5:53,883,942-54,310,590

Gene Map Locus

5q11.2

Description

ARL15 gene encodes a GTP-binding protein. The exact function of ARL15 protein is unknown but its localization in certain cell organelles suggests a role in protein trafficking. Variants in ARL15 gene are associated with glomerular filtration rate, HDL cholesterol levels, reticulocyte count, type 2 diabetes, waist-hip ratio, and adiponectin levels.

Epidemiology in the Arab World

View Map

United Arab Emirates

Variant Name	Country	Genomic Location	Clinvar Clinical Significance	CTGA Clinical Significance	Condition(s)	HGVS Expressions	dbSNP	Clinvar
NM_019087.2:c.463-88877=	United Arab Emirates	NC_000005.10:g.53975590=		Association	Type 2 Diabetes Mellitus	NM_019087.2:c.463-88877=; NP_061960.1:p.?	702634
NM_019087.3:c.463-100106A>G	United Arab Emirates	NC_000005.10:g.53986819T>C		Association	Type 2 Diabetes Mellitus; Obesity	NM_019087.3:c.463-100106A>G; NP_061960.1:p.?	1664789

Download Table

External Links

https://www.genecards.org/cgi-bin/carddisp.pl?gene=arl15

Contributors

Asha Deepthi: 16.09.2021
Asha Deepthi: 19.08.2021

Edit History

Pratibha Nair: 09.02.2023
Asha Deepthi: 16.09.2021
Asha Deepthi: 19.08.2021

Back to search Result