Potassium Channel, Subfamily K, Member 16

Alternative Names

  • KCNK16
  • TWIK-Related Alkaline Ph-Activated K+ Channel 1
  • TALK1

Associated Diseases

Type 2 Diabetes Mellitus
Back to search Result
OMIM Number

607369

NCBI Gene ID

83795

Uniprot ID

Q96T55

Length

8,403 bases

No. of Exons

8

No. of isoforms

4

Protein Name

Potassium channel subfamily K member 16

Molecular Mass

34153 Da

Amino Acid Count

309

Genomic Location

chr6:39,314,565-39,322,967

Gene Map Locus
6p21.2

Description

The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is expressed predominantly in the pancreas and is activated at alkaline pH. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [From RefSeq]

Epidemiology in the Arab World

View Map
Variant NameCountryGenomic LocationClinvar Clinical SignificanceCTGA Clinical Significance Condition(s)HGVS ExpressionsdbSNPClinvar
NM_001135105.1:c.661+374=United Arab EmiratesNC_000006.12:g.39316408=AssociationType 2 Diabetes MellitusNM_001135105.1:c.661+374=; NP_001128577.1:p.?3734618
© CAGS 2024. All rights reserved.