Epilepsy, Idiopathic Generalized, Susceptibility to, 15

Alternative Names

  • EIG15
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WHO-ICD-10 version:2010

Diseases of the nervous system

Episodic and paroxysmal disorders

OMIM Number

618357

Mode of Inheritance

Autosomal dominant

Gene Map Locus

9q21.13

Description

Susceptibility to idiopathic generalized epilepsy-15 (EIG15) is an autosomal dominant seizure disorder characterized by onset of variable types of seizures in the first decade. Absence seizures are the most common manifestation, but most patients also develop other types, including clonic or generalized tonic-clonic seizures. EEG tends to show 3-Hz spike-wave discharges, whereas brain imaging is normal. The majority of patients also have developmental delay associated with impaired intellectual development apparent from infancy or early childhood. [From OMIM]

Epidemiology in the Arab World

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Subject IDCountrySexFamily HistoryParental ConsanguinityHPO TermsVariantZygosityMode of InheritanceReferenceRemarks
618357.1United Arab EmiratesFemaleYesYes Attention deficit hyperactivity disorder...NM_006914.3:c.196C>THeterozygousAutosomal, DominantSaleh et al. 2021 Affected cousin. Mot...
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