Protein Kinase D1

Alternative Names

PRKD1
Protein Kinase C, Mu
PRKCM
PKC-MU
Protein Kinase D
PKD

Length

351,369 bases

No. of Exons

No. of isoforms

Protein Name

Serine/threonine-protein kinase D1

Molecular Mass

101704 Da

Amino Acid Count

912

Genomic Location

chr14:29,576,478-29,927,846

Gene Map Locus

14q12

Description

The protein encoded by this gene is a serine/threonine protein kinase involved in many cellular processes, including Golgi body membrane integrity and transport, cell migration and differentiation, MAPK8/JNK1 and Ras pathway signaling, MAPK1/3 (ERK1/2) pathway signaling, cell survival, and regulation of cell shape and adhesion. [From RefSeq]

Epidemiology in the Arab World

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Variant Name	Country	Genomic Location	Clinvar Clinical Significance	CTGA Clinical Significance	Condition(s)	HGVS Expressions	dbSNP	Clinvar
NM_001330069.1:c.265-35758T>C	Arab; United Arab Emir...	NC_000014.9:g.29761432A>G		Association	Type 2 Diabetes Mellitus	NG_052879.1:g.171262T>C; NM_001330069.1:c.265-35758T>C; NP_001316998.1:p.?	1953722
NM_001330069.1:c.265-77429A>C	United Arab Emirates	NC_000014.9:g.29803103T>G		Association	Type 2 Diabetes Mellitus	NG_052879.1:g.129591A>C; NM_001330069.1:c.265-77429A>C; NP_001316998.1:p.?	10144903

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External Links

https://www.genecards.org/cgi-bin/carddisp.pl?gene=prkd1

Contributors

Asha Deepthi: 13.04.2022

Edit History

Pratibha Nair: 08.02.2023
Asha Deepthi: 13.04.2022

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