125853.G.10.2

Country

Lebanon

HPO Terms

Diabetes mellitus; Nephropathy

Sex

Unknown

Subject Variants

Variant Name	Allele Count	Allele Frequency	Associated Disease
APOE*2 Allele NM_000041.4:c.[388=;526C>T]	217	NA	Type 2 Diabetes Mellitus
APOE*3 Allele NM_000041.4:c.[388=;526=]	630	NA	Type 2 Diabetes Mellitus
APOE*4 Allele NM_000041.4:c.[388T>C;526=]	346	NA	Type 2 Diabetes Mellitus

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Remarks

Group consisting of 597 T2DM patients with nephropathy. Study indicated that E2 & E3 alleles modify lipid profile and contribute to the risk of developing diabetic nephropathy in T2DM patients

References

Atageldiyeva et al, 2019

Related Subjects

Subject Id	Country	HPO Terms	Sex	Family History	Parental Consanguinity	Remarks
125853.G.10.1	Lebanon	Diabetes mellitus	Unknown			Group consisting of 825 T2DM patients without nephropathy
125853.G.10.3	Lebanon		Unknown			Group consisting of 1389 control subjects

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