608320.G.2.1

United Arab Emirates

Myocardial infarction; Abnormal coronary artery morphology; Type II diabetes mellitus; Abnormal circulating lipid concentration; Hypertension

Unknown

Variant Name	Allele Count	Allele Frequency	Associated Disease	Associated Gene
NM_000237.2:c.776-172G>A	NA	0.137	Coronary Artery Disease, Autosomal Dominant, 1
NR_135674.1:n.45+8018T>C	NA	0.453	Coronary Artery Disease, Autosomal Dominant, 1

160 subjects with CAD from a study consisting of 914 individuals. Two SNPs showed association with CAD.

Related Subjects

Subject Id	Country	HPO Terms	Sex	Family History	Parental Consanguinity	Remarks
608320.G.2.2	United Arab Emirates		Unknown			Group consisting of 332 control subjects.
608320.G.2.3	United Arab Emirates	Myocardial infarction; Abnormal coronary artery morphology; Type II diabetes mellitus; Abnormal circulating lipid concentration; Hypertension	Unknown			Study with 914 individuals. 22 SNPs showed association with one or more cardio-metabolic traits in CAD patients (n=160). Following cardio-metabolic traits were studied: BMI, waist circumference, height, systolic blood pressure, diastolic blood pressure, fasting blood glucose, random blood glucose, HbA1c, total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride.