The WDR72 gene is located on chromosome 15. Its 19 coding exons and introns occupy a space of around 246 Kb. The mature WDR72 protein is made up of 1102 amino acids and weighs 123 kDa. WDR72 is predicted to contain seven WD40 domains. These domains are typified by minimally conserved runs of about 40 amino acids bracketed by glycine-histidine and tryptophan-aspartic acid. These domains tend to form the blades of beta propeller structures with four to eight blades, which in turn, act as docking platforms for transient protein-complex formations.