Insulin-Like Growth Factor 2 mRNA-Binding Protein 2

Alternative Names

  • IGF2BP2
  • IGF2 MRNA-Binding Protein 2
  • IMP2
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OMIM Number

608289

NCBI Gene ID

10644

Uniprot ID

Q9Y6M1

Length

181,926 bases

No. of Exons

24

No. of isoforms

6

Protein Name

Insulin-like growth factor 2 mRNA-binding protein 2

Molecular Mass

66121 Da

Amino Acid Count

599

Genomic Location

chr3:185,643,131-185,825,056

Gene Map Locus
3q27.2

Description

IGF2BP2 gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. [From RefSeq]

Epidemiology in the Arab World

View Map
Variant NameCountryGenomic LocationClinical SignificanceCondition(s)HGVS ExpressionsdbSNPClinvar
NC_000003.12:g.185811292A>CLebanonchr3:185811292Diabetes Mellitus, Noninsulin-DependentNG_011602.1:g.18748T>G1470579
NM_006548.6:c.239+29254C>ALebanonchr3:185793899Risk factorDiabetes Mellitus, Noninsulin-DependentNG_011602.1:g.36141C>A; NM_006548.6:c.239+29254C>A44029602435
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